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NIR Responsive Plasmonic Nanostructures for TNBC

Status: New

Lab/Organization
Name & address of the Laboratory/Organization Indian Institute of Technology (IIT), Mandi
Website address www.iitmandi.ac.in
Affiliated to which Department/Ministry Indian Institute of Technology (IIT)
CSR Registration Number CSR00057737
Registration under 12A AAALI0149JF20221
Registration under 80G Exemption under notification vide no. CCIT(E)/order u/s 80G(2)(a)(iiif)/2016-17/1480
Name of the CSR Nodal Prof. Varun Dutt
Contact information of CSR Nodal +91 1905 27945, dora@iitmandi.ac.in
Principal Investigator Dr. Amit Jaiswal, j.amit@iitmandi.ac.in
AJ lab | IIT Mandi | nanobiotech | India | Amit Jaiswal
Co- Principal Investigator (Co-PI)
Project Detail
Objective on the basis of need

To develop a NIR-responsive cancer theranostic platform with plasmonic nanorattles for targeted bioimaging and photothermal therapy.

Executive summary of the proposed project (In 250 words)

This project aims to tackle triple-negative breast cancer (TNBC) by developing theranostic nanoparticles composed of gold nanorattles. These nanoparticles will enable targeted delivery of antagomiRs, combined with photothermal therapy and SERS-based bioimaging. The project leverages nanotechnology for precise treatment and monitoring, reducing side effects and improving patient outcomes.

Technology Readiness Level (If not a new project but an advancement of existing know how) TRL 3
Outomes or Deliverables

Development of gold nanorattle-based nanoparticles for cancer therapy. Improved imaging and therapeutic outcomes for TNBC patients.

Project aligned with which most relevant UN SDGs Goal 3 - Good Health & Well-Being
Goal 9 - Industry, Innovation & Infrastructure
Duration (In years) 3 years
Expected Impact

Enhanced survival rates and quality of life for TNBC patients. Breakthroughs in cancer diagnostics and therapeutics.

Implementation model (self- implemented/ outsourced partnership) Laboratory development and clinical collaboration.
Total Budget (Recurring +Non-Recurring Expenses) INR 60 lakhs