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Development of Hadjod-Based 3D-Bioprinting Formulation for Treating Osteoarthritic Lesions

Status: New

Lab/Organization
Name & address of the Laboratory/Organization Indian Institute of Technology (IIT), Mandi
Website address www.iitmandi.ac.in
Affiliated to which Department/Ministry Indian Institute of Technology (IIT)
CSR Registration Number CSR00057737
Registration under 12A AAALI0149JF20221
Registration under 80G Exemption under notification vide no. CCIT(E)/order u/s 80G(2)(a)(iiif)/2016-17/1480
Name of the CSR Nodal Prof. Varun Dutt
Contact information of CSR Nodal +91 1905 27945, dora@iitmandi.ac.in
Principal Investigator Dr. Sumit Murab, sumitmurab@iitmandi.ac.in
Murab Group
Co- Principal Investigator (Co-PI)
Project Detail
Objective on the basis of need

To develop and optimize a Hadjod-infused bioink for 3D bioprinting to treat osteoarthritic lesions, promoting cartilage regeneration and reducing inflammation.

Executive summary of the proposed project (In 250 words)

This project utilizes Cissus quadrangularis (Hadjod), known for its muscle and bone-strengthening properties, in a 3D-bioprinting formulation for localized treatment of osteoarthritis. The bioink will enable the creation of personalized scaffolds for precise treatment, reducing systemic side effects and promoting cartilage healing.

Technology Readiness Level (If not a new project but an advancement of existing know how) TRL 5 - Technology validated in a relevant environment.
Outomes or Deliverables

Personalized scaffolds for osteoarthritis treatment. Reduction in inflammation and progression of osteoarthritis. Enhanced cartilage regeneration.

Project aligned with which most relevant UN SDGs Goal 3 - Good Health & Well-Being
Goal 9 - Industry, Innovation & Infrastructure
Duration (In years) 2 years
Expected Impact

Improved mobility and quality of life for osteoarthritis patients. Advancement in personalized medical solutions.

Implementation model (self- implemented/ outsourced partnership) Academic collaboration and laboratory-based development.
Total Budget (Recurring +Non-Recurring Expenses) INR 28.80 lakhs